What are NMDA Antagonists and What do they do
NMDA Antogonists are molecules which act as antagonists at the
NMDA
receptor in the
Central Nervous System.
In Theory, NMDA Antagonists should
- prevent the development of Tolerance to Medications -
- this should, in theory,
- make
continuing doses have the same effects as the first dose, so there will be no
need to raise the dose over a period of time
- prevent
the development of addiction
- prevent
withdrawal from occurring when the drug is removed.
- allow
an enormous decrease in side effects caused by having to keep raising the dose over
a period of time
- save a
ton of money for people using expensive medications
NMDA Antagonists may also,
- reverse tolerance, allowing
people to lower the dose they have been using, with savings in drug costs and
decreased side effects
- allow
people to lower the dose or stop the drug without going through withdrawal
- allow
addicts to stop using the drug without going through withdrawal
- stop
addiction, by removing the 'reward' mediated by the NMDA receptors
Anti-addiction Effect
- allowing someone to think about the drug rationally, and control their use of it
rationally, without having their judgment crippled by the distorting effects of
the 'reward mechanism'
which is abnormal in addiction.